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Cough Reduction in IPF With Nalbuphine ER (CORAL) 27 Jun 2025 · The main purpose of the study is to evaluate the effect of NAL ER on 24-hour cough frequency using objective digital cough monitoring and to assess safety and tolerability …
Clinical Trial: CORAL - AHA/ASA Journals The CORAL study (Cardiovascular Outcomes in Renal Atherosclerotic Lesions) is a prospective clinical trial of 947 participants with atherosclerotic renal artery stenosis randomized to optimal …
Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) 3 Jan 2018 · The CORAL trial compared the incidence of cardiovascular and renal adverse events for medical therapy alone with medical therapy plus renal-artery stenting in patients with …
Roll-in Experience from the Cardiovascular Outcomes with Renal ... The Cardiovascular Outcomes with Renal Atherosclerotic Lesions (CORAL) study is a multicenter randomized clinical trial examining whether renal artery stenting modifies the natural history for …
Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis 2 Jan 2014 · The Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) study was a multicenter, open-label, randomized, controlled trial that compared medical therapy alone …
Trevi Therapeutics Announces Positive Outcome from Sample … 12 Dec 2024 · Phase 2b IPF Chronic Cough Trial Design (CORAL): The CORAL trial is a double-blind, randomized, placebo-controlled, parallel-arm trial evaluating three doses of Haduvio …
Drug significantly reduces common cough in IPF patients 9 Jul 2025 · Trevi Therapeutics has announced positive topline results from its Phase IIb CORAL trial of Haduvio for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis …
Trevi Therapeutics Announces Positive Topline Results from the … 2 Jun 2025 · --Trevi Therapeutics, Inc., a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ for the treatment of chronic cough in patients with …
Quality of Life Effects of Renal Artery Stenting Versus Medical … Methods: We performed a pre-specified quality of life sub-study of the CORAL trial-multicenter, randomized, open-label trial of renal-artery stenting versus medical therapy in patients with …
Trevi Therapeutics Announces Positive Topline Results from the … 2 Jun 2025 · The primary endpoint in the CORAL trial was achieved, demonstrating statistically significant reductions in 24-hour cough frequency across all dose groups at Week 6.