2 Metylbutan 1 Ol

2-Methylbutan-1-ol: A Comprehensive Q&A

Introduction:

2-Methylbutan-1-ol, also known as isoamyl alcohol, is a branched-chain aliphatic alcohol with the chemical formula C₅H₁₂O. It's a colorless liquid with a characteristic pungent, slightly fruity odor, often described as reminiscent of bananas or fusel oil. While perhaps not a household name, understanding 2-methylbutan-1-ol is crucial for several industries, from fragrance and flavor production to chemical synthesis. This Q&A will explore its properties, applications, and safety considerations.

I. Chemical Structure and Properties:

Q: What is the chemical structure of 2-methylbutan-1-ol?

A: 2-Methylbutan-1-ol has a five-carbon chain with a methyl group (CH₃) branching off the second carbon and a hydroxyl group (-OH) attached to the first carbon. This specific arrangement leads to its unique properties.

Q: What are the key physical and chemical properties of 2-methylbutan-1-ol?

A: It's a colorless liquid at room temperature, slightly soluble in water, and readily soluble in most organic solvents. Its boiling point is relatively low (around 130-132°C), indicative of its relatively weak intermolecular forces. It's flammable and has a relatively low flash point, requiring careful handling. Its reactivity is typical of primary alcohols; it can undergo oxidation to form aldehydes and carboxylic acids, esterification to form esters, and dehydration to form alkenes.

II. Production and Synthesis:

Q: How is 2-methylbutan-1-ol produced industrially?

A: Industrially, it is often produced through the hydroformylation of isobutene followed by hydrogenation. This involves reacting isobutene with carbon monoxide and hydrogen in the presence of a catalyst (typically a rhodium or cobalt complex) to produce an aldehyde, which is then hydrogenated to the alcohol. Other methods involve fermentation processes using specific strains of bacteria or yeasts, but these are generally less efficient for large-scale production.

Q: Are there any naturally occurring sources of 2-methylbutan-1-ol?

A: Yes, 2-methylbutan-1-ol is a component of fusel oils, which are byproducts of alcoholic fermentation. Fusel oils contribute to the characteristic "hangovers" associated with consuming excessive amounts of certain alcoholic beverages. It is also found in small quantities in various fruits and essential oils, contributing to their complex aroma profiles.

III. Applications and Uses:

Q: What are the main applications of 2-methylbutan-1-ol?

A: Its primary use lies in the production of esters, particularly isoamyl acetate, which is a crucial ingredient in banana flavoring and various fragrances. It's also used as a solvent in various industrial applications, including the production of paints, coatings, and inks. Furthermore, it serves as an intermediate in the synthesis of pharmaceuticals and other fine chemicals. Its use as a solvent for resins and oils is also noteworthy.

IV. Safety and Handling:

Q: What are the safety concerns associated with handling 2-methylbutan-1-ol?

A: As with many organic solvents, 2-methylbutan-1-ol is flammable and should be handled with care away from ignition sources. It can cause irritation to the skin, eyes, and respiratory tract. Inhalation of significant amounts can lead to dizziness, headaches, and even more severe neurological effects. Appropriate personal protective equipment (PPE), including gloves, eye protection, and respiratory protection, should be used when handling this chemical. Proper ventilation is also crucial.

Q: What are the environmental concerns related to 2-methylbutan-1-ol?

A: While not considered highly toxic to the environment, release of large quantities of 2-methylbutan-1-ol can contribute to air and water pollution. Its biodegradability is relatively moderate, meaning it can persist in the environment for some time. Responsible disposal and minimizing waste are essential for environmental protection.

Conclusion:

2-Methylbutan-1-ol is a versatile chemical compound with significant applications in various industries. Its unique chemical structure and properties make it valuable in flavor and fragrance production, as a solvent, and as an intermediate in chemical synthesis. However, proper safety measures must always be observed due to its flammability and potential health hazards. Understanding its properties and handling guidelines is crucial for safe and responsible use.

FAQs:

1. What is the difference between 2-methylbutan-1-ol and other isomers like 3-methylbutan-1-ol? The position of the methyl group and hydroxyl group significantly alters the molecule's properties, influencing its reactivity, boiling point, and odor. Isomers have the same molecular formula but different structural arrangements.

2. Can 2-methylbutan-1-ol be used in food applications? While its esters are widely used in food flavoring, the use of 2-methylbutan-1-ol itself in food is limited due to its relatively strong odor and potential toxicity concerns at high concentrations. Strict regulations govern its use.

3. What are the typical storage conditions for 2-methylbutan-1-ol? It should be stored in a cool, dry, well-ventilated area, away from ignition sources and incompatible materials. Sealed containers are necessary to prevent evaporation and contamination.

4. What are the common methods for analyzing the purity of 2-methylbutan-1-ol? Gas chromatography (GC) is commonly used to determine its purity and identify any impurities present. Other techniques like nuclear magnetic resonance (NMR) spectroscopy can provide structural confirmation.

5. What are the potential health effects of long-term exposure to 2-methylbutan-1-ol? Chronic exposure can lead to cumulative effects on the nervous system, liver, and kidneys. Specific health impacts depend on the concentration and duration of exposure. Regular health checks are advisable for individuals with frequent occupational exposure.

Search Results:

2-Methyl-1-butanol | 137-32-6 - ChemicalBook 27 Jan 2025 · 2-Methyl-1-butanol (CAS 137-32-6) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.

2-Methyl-1-butanol, (+)- | C5H12O | CID 637572 - PubChem 2-Methyl-1-butanol, (+)- | C5H12O | CID 637572 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2-Methyl-1-butanol, 98%, Thermo Scientific Chemicals 2-Methyl-1-butanol is a volatile metabolite produced by a number of different plant species. Used as a solvent in organic synthesis (introduction of active amyl group), in lubricants, plasticizers, additives for oils & paints. It is also employed as a perfuming agent.

2-Methylbutan-1-ol | C5H12O - ChemSpider ChemSpider record containing structure, synonyms, properties, vendors and database links for 2-Methylbutan-1-ol, 137-32-6, QPRQEDXDYOZYLA-UHFFFAOYSA-N Accessed: Simple

2-Methylbutan-1-ol | CAS#:137-32-6 | Chemsrc - 化源网 2 Jan 2024 · Chemsrc provides 2-Methylbutan-1-ol(CAS#:137-32-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 2-Methylbutan-1-ol are included as well. CAS Number Search

2-Methyl-1-butanol natural, 99 , FG 137-32-6 - MilliporeSigma Comparative study of two indoor microbial volatile pollutants, 2-Methyl-1-butanol and 3-Methyl-1-butanol, on growth and antioxidant system of rice (Oryza sativa) seedlings. : This article evaluates the impact of 2-methyl-1-butanol and its structural isomer on the growth and stress responses of rice seedlings, offering insights into the environmental and biological effects of these …

2-Methyl-1-butanol = 99 , FG 137-32-6 - MilliporeSigma Volatile profiles of members of the USDA Geneva Malus Core Collection: utility in evaluation of a hypothesized biosynthetic pathway for esters derived from 2-methylbutanoate and 2-methylbutan-1-ol.

2-methyl-1-butanol, 137-32-6 - The Good Scents Company PubMed:Volatile Profiles of Members of the USDA Geneva Malus Core Collection: Utility in Evaluation of a Hypothesized Biosynthetic Pathway for Esters Derived from 2-Methylbutanoate and 2-Methylbutan-1-ol.

2-methylbutan-1-ol | C5H12O | Reactory Names, description, applications, structure, physical properties and reactions for the compound "2-methylbutan-1-ol".

2-Methyl-1-butanol | C5H12O | CID 8723 - PubChem 2-methylbutan-1-ol is a primary alcohol that is isopentane substituted by a hydroxy group at position 1. It has a role as a Saccharomyces cerevisiae metabolite. It is an alkyl alcohol and a primary alcohol. It derives from a hydride of an isopentane.

2-Methylbutan-1-ol - fudabio.com 2-methyl-1-butanol: English name: 2-Methylbutan-1-ol: Molecular formula: C5H12O: Molecular weight: 88.15: Melting point-70℃ Boiling point: 130℃ Flash point: 43.3℃ Density (water =1) 0.809 (Air =1) 3.0: Solubility: Slightly soluble in water, miscible with ethanol, ethyl acetate, butyl acetate, ketone, ether, benzene, toluene, gasoline, etc ...

2-Methyl-1-butanol - Wikipedia 2-Methyl-1-butanol (IUPAC name, also called active amyl alcohol) is an organic compound with the formula CH 3 CH 2 CH (CH 3)CH 2 OH. It is one of several isomers of amyl alcohol.

2-METHYLBUTAN-1-OL | CAS 137-32-6 - Matrix Fine Chemicals DL-2-METHYL-1-BUTANOL. CAS Number: 137-32-6. Molecular Weight: 88.15. Formula: C5H12O. SMILES: CCC(C)CO. Preferred IUPAC Name: 2-METHYLBUTAN-1-OL. InChIKey: InChIKey=QPRQEDXDYOZYLA-UHFFFAOYNA-N. Categories: Aromatic Heterocycles, Alcohols, Primary Alcohols. Synonyms:

1-Butanol, 2-methyl-, (S)- - NIST Chemistry WebBook 2-Methyl-1-butanol; 1-Butanol, 2-methyl-Other names: l-2-Methyl-1-butanol; (S)-(-)-2-Methyl-1-butanol; (S)-2-methylbutan-1-ol Permanent link for this species. Use this link for bookmarking this species for future reference. Information on this page: Phase change data; Mass spectrum (electron ionization) References; Notes; Other data available ...

2-methylbutan-1-ol (CHEBI:48945) - EMBL-EBI Post-cutting 1-methylcyclopene (1-MCP) application to fresh-cut cantaloupe was evaluated for its effects on quality attributes, phytochemical content and aroma volatiles.

2-Methyl-1-butanol = 99 137-32-6 - MilliporeSigma Aldrich-133051; 2-Methyl-1-butanol >=99%; CAS Number: 137-32-6; Linear Formula: C2H5CH(CH3)CH2OH; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich.

1-Butanol, 2-methyl- - NIST Chemistry WebBook IUPAC Standard InChI: InChI=1S/C5H12O/c1-3-5(2)4-6/h5-6H,3-4H2,1-2H3 Copy IUPAC Standard InChIKey: QPRQEDXDYOZYLA-UHFFFAOYSA-N Copy CAS Registry Number: 137-32-6

2-Methyl-1-butanol natural, 99 , FG 137-32-6 - MilliporeSigma Gene transfer using adeno-associated viral (AAV) vectors has been successfully applied in the retina for the treatment of inherited retinal dystrophies. Recently, microRNAs have been exploited to fine-tune transgene expression improving therapeutic outcomes. Here we evaluated the ability of retinal-expressed.

(S)-(-)-2-Methyl-1-butanol | C5H12O | CID 2723602 - PubChem 14 Oct 2021 · (S)-(-)-2-Methyl-1-butanol | C5H12O | CID 2723602 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Amyl alcohol - Wikipedia Three of these alcohols, 2-methyl-1-butanol, 2-pentanol, and 3-methyl-2-butanol (methyl isopropyl carbinol), contain stereocenters, and are therefore chiral and optically active. The most important amyl alcohol is isoamyl alcohol, the chief one generated by fermentation in the production of alcoholic beverages and a constituent of fusel oil.

2 Metylbutan 1 Ol

2-Methylbutan-1-ol: A Comprehensive Q&A

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